GLENROSE HOSPITAL FOUNDATION | 11 What happens when we stop asking what can’t be done, and start asking what might be possible? We sat down with Dr. Jessica D’Amico to talk about the science and people driving the future of neurorehabilitation. Glenrose Hospital Foundation (GHF): What first drew you to neuroscience and rehabilitation research? Dr. Jessica D’Amico (JD): I’ve always been someone who wanted to understand how things work, but more importantly, how they can work better. That curiosity naturally drew me to neuroscience. As I learned more about the brain and spinal cord, I became fascinated by the fact that an injury can change someone’s life in an instant, and yet the nervous system still has an incredible capacity to adapt and recover. That possibility has motivated me ever since. As my career progressed, I realized I wasn’t interested in doing research simply for the sake of publishing papers. I wanted to do research that could genuinely change the way people recover after neurological injury. That led me into rehabilitation research, where every scientific question has the potential to translate into something meaningful for a person trying to regain their independence. GHF: Was there a moment that made this work personal for you? JD: There wasn’t one defining moment; it was a series of experiences. But my perspective became much more personal when my grandmother had a stroke. She came to live with our family, and we helped care for her as she navigated life after her stroke. Watching someone you love work so hard to regain everyday abilities gives you a completely different appreciation for rehabilitation. You see that recovery isn’t just about improving strength or movement. It’s about restoring independence, dignity, and the ability to participate in the moments that matter most. Later, as I began working with people living with spinal cord injury and stroke, those experiences reinforced what I’d witnessed firsthand. I met individuals whose determination continually challenged our assumptions about recovery and reminded me that there is always more we can do. GHF: You lead the Clinical Trials and Research Platform at the Glenrose. What does that work look like? JD: My role is to help ensure that when people walk through the doors of the Glenrose, they know they are in a place that’s at the forefront of advancing rehabilitation. I work with clinicians, researchers, industry partners, and funding agencies to bring innovative rehabilitation technologies and therapies into the hospital so they can be evaluated safely and rigorously. That can mean designing clinical trials, securing research funding, mentoring research staff and students, supporting clinicians, or helping patients participate in studies that may shape the future of rehabilitation. Ultimately, my goal is to bridge the gap between research discoveries and everyday patient care. Today, we're seeing growing evidence that the nervous system is far more adaptable than we once believed. GHF: For someone unfamiliar with your work, what are you researching? JD: Our research focuses on helping people recover after neurological injuries such as spinal cord injury and stroke. We study new rehabilitation approaches, from technologies such as non-invasive spinal cord stimulation to digital rehabilitation platforms. We carefully evaluate these approaches through clinical research to understand whether they’re safe, effective, and practical to implement in real-world healthcare. GHF: What are you trying to achieve through this research? JD: I’m trying to help redefine what’s possible after neurological injury. For decades, many people living with spinal cord injury or stroke were told that recovery plateaued after a certain point. That if function hadn’t returned within months, it probably never would. Today, we’re seeing growing evidence that the nervous system is far more adaptable than we once believed. Even years after an injury, it can continue to change, relearn, and recover when given the right combination of therapy and technology. That’s incredibly exciting because it shifts the conversation from managing disability to maximizing recovery. Support from the Glenrose Hospital Foundation has also been instrumental in creating opportunities to bring new technologies, build research capacity, and accelerate innovation that directly benefits patients.
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